Stay Positive


"In the midst of winter I finally learned that there was in me an invincible summer."

- Alert Camus








Thursday, October 30, 2014

What are some of the symptoms of multiple sclerosis


During MS the body's immune system turns on its own nerves causing debilitating muscle problems.

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Multiple Sclerosis Discovery Forum





New drug added to the Drug-Development Pipeline
We recently added a new drug to our Drug-Development Pipeline database. The drug, ATX-MS-1467, is an immunomodulator. Click the link above to view.
News & Future Directions
 
No Causal Link Found Between Vaccines and MS
A large case-control study showed no causal link between current vaccines and the risk of MS or other CNS demyelinating disease, but there was a short-term increased risk in younger patients.
Multiple Sclerosis Discovery Podcast -- Episode 18 with Dr. Samuel Ludwin
In the latest episode of the MSDF podcast, we interview Dr. Samuel Ludwin about new approaches to remyelinating therapies. We post each episode at http://www.msdiscovery.org/news/podcasts. You may also subscribe to the podcast via iTunes or your favorite podcast app. To subscribe in iTunes, simply go to the iTunes store, search "Multiple Sclerosis Discovery," click on the link to the show, and then click "subscribe."
MS Research Roundup: October 28, 2014
Rare Brain Disease Death Reported for Dimethyl Fumarate; Using Arms and Legs After Spinal Cord Injury; How to Sell Bogus Drugs
MS Research Roundup: October 22, 2014
A Better CRISPR Mouse; Number Needed to Treat; Ann Romney to Raise $50M for Neuroscience Research
MS Patient, Ph.D.
 
MS Patient, Ph.D.: Lightning (and the Ice Bucket Challenge) Doesn’t Strike Twice
The ice bucket challenge has raised $100 million for the Amyotrophic Lateral Sclerosis Association; should the multiple sclerosis community try to copy this campaign?
Forums & Comments
 
Share your thoughts about any of MS Discovery Forum's articles and discussion topics. Your viewpoints will enrich the site for everyone.

Recent comments have come from Bob Finn, Barbara van Amerongen, and B. Krone.
Papers
 
Visit Papers of the Week for the latest citations from PubMed, and then post a comment or read a colleague's. View Editors' Picks selections and Classic Papers, suggested by members of the community. Submit your own suggestions to help build this catalog of milestone papers.
Professional Resources
 
Visit the site’s Professional Resources section to access our listings of
•Meetings and Events

  NEW! UCSF Seminar: "The needle in the haystack: Searching for target antigens of the adaptive immune response in MS." - Oct 31

  American Academy of Neurology Fall Conference 2014  - Oct 31-Nov 2

  12th International Society of Neuroimmunology Congress - Nov 9-13

  Neuroscience 2014 - Nov 15-19

  Blood Brain Barrier Meeting - Dec 10-13

  Keystone Symposium: Viral Immunity - Jan 11-16
 
  Keystone Symposium: Neuroinflammation in Diseases of the Central Nervous System - Jan 25-30 (Abstract Submission Deadline Oct 23)

 Keystone Symposium: Autoimmunity and Tolerance - Feb 3-8 (Abstract Submission Deadline Nov 4)

  Keystone Symposium: Neuroepigenetics - Feb 22-26 (Abstract Submission Deadline Nov 19)

  Glial Biology: Functional Interactions Among Glia & Neurons (Gordon Research Seminar) - Feb 28-Mar 1 (Abstract Submission Deadline Jan 31)

  NEW! Keystone Symposium: Gut Microbiota Modulation of Host Physiology: The Search for Mechanism - Mar 1-6 (Abstract submission deadline Dec 2)

  NEW! Keystone Symposium: Dendritic Cells and Macrophages Reunited - Mar 8-13 (Abstract submission deadline Dec 10)

  American Society for Neurochemistry 46th Annual Meeting - Mar 14-18 (Early Registration Deadline Jan 30 )

  2015 Annual Meeting of the Consortium of the Multiple Sclerosis Centers - May 27-30 (Abstract submission deadline Jan 9)

  FOCIS 2015 (Federation of Clinical Immunology Societies) - Jun 24-27

  ISN-APSN Biennial Meeting - Aug 23-27

Are we missing something? Post it to our website! Just go to the professional resources tab at msdiscovery.org, click on "Meetings and Events," and click the "Submit new item" button. Then simply log in and post your meeting. We're happy even to list departmental seminars. If you prefer, you can also email your items to editor@msdiscovery.org.
•Funding Opportunities

  Round 2 Grant Awards from the International Progressive MS Alliance - Application period opens Nov 3

  ECTRIMS Multiple Sclerosis Clinical Training Fellowship Programme - Application due Dec 1

  ECTRIMS Postdoctoral Research Fellowship Exchange Programme - Application due Dec 1

  National MS Society: Health Care Delivery And Policy Research Contracts - Application due Jan 7, 2015

  ECTRIMS Multiple Sclerosis Nurse Training Fellowship Programme - Application due Feb 1, 2015

  ECTRIMS-MAGNIMS Fellowship in Magnetic Resonance Imaging in MS - Application due Feb 1, 2015  
•Jobs

  Mellen Center MS Neurologist - Las Vegas, NV & Weston, FL

  MS Neurologist: Massachusetts General Hospital

  Research Associate: Tisch MS Research Center of New York
•Bulletin Board

  Seeking Nominations: Dystel Prize for MS Research - Deadline Oct 23
Research Resources
 
•
The Data Visualization section presents MS-related data in new ways, making it easy for viewers to discover unexpected relationships.
•
The Drug-Development Pipeline consolidates key information about compounds under investigation for therapeutic use.
NEW! This past week, we added 1 new trial, we updated information on 2 other trials, and we've added 11 other pieces of information. The drugs with important additions and changes are dalfampridine, dimethyl fumarate, fingolimod, interferon beta-1a, interferon beta-1b, mitoxantrone, natalizumab, and teriflunomide.

We've also added a new entry for ATX-MS-1467, which contains information on 3 trials as well as 23 other pieces of information.

In summary, for the month of October we added 6 new trials, we updated information on 8 other trials, and we added 85 other pieces of information. The drugs with important additions and changes are ATX-MS-1467, daclizumab, dalfampridine, dimethyl fumarate, fingolimod, glatiramer acetate, interferon beta-1a, interferon beta-1b, laquinimod, masitinib, mitoxantrone, natalizumab, rituximab, and teriflunomide.
•
Tissue Repositories lists features of the world’s tissue repositories and brain banks, including rules of engagement and contact information. Let us know about additional repositories to include.
•
Animal Models summarizes the promises and pitfalls of animal models used in MS research.

NEW! We recently added a new animal model to our collection: the Zebrafish.
•
Clinical Trials lists sources of information about MS clinical trials.




Source: http://us4.campaign-archive1.com/?u=2820dfcfd46c6efd776966448&id=e0317aee34






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Researching multiple sclerosis





MS Discovery Forum @MSDForum · Oct 28
New #MS Discovery podcast features Dr. Samuel Ludwin on new approaches to remyelination. 
Find it here http://ow.ly/DpJzq or on iTunes


Detailed information on investigational drug ATX-MS-1467 Just added to the MSDF Drug-Development Pipeline


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Tuesday, October 28, 2014

Concerns you might have about m.s.


 MultipleSclerosisnet‏@MS_HealthUnion
Common Sense from Experience vs Research Studies: 
http://multiplesclerosis.net/?p=5052

The frequently veiled side of MS is the psychic beating it inflicts on its victims. 


 18 hours ago
Tips for Managing MS Cramps and Spasms: Meditate to let your mind and muscle cramps drift away. .



 · Oct 26
Need help explaining MS to friends & family? Check out the "What is MS" page:



 · Oct 26
Using Food As Medicine. Some available options (as always, consult w/ your Dr. before beginning any new food plan.)


 · Oct 26
Tips for Managing MS Cramps and Spasms: Try an old natural remedy, Pickle juice!


Tips for Managing MS Cramps and Spasms: Stay Hydrated.


Tips for Managing MS Cramps and Spasms: Apply an ice pack to your muscles:


Tips for Managing MS Cramps and Spasms: Deep Breathing.


Tips for Managing MS Cramps and Spasms: Make sure to stretch.

Make sure to stay aadequately hydrated while exercising. Drinking everages that contain electrolytes can really help.

You know you have MS when people assume you are drunk!



 · Oct 25
What's the secret behind getting up & moving? BC I’m entering that extended period w/ no commitment & no motivation.


 · Oct 25
I started researching clinical trials and came across one that had to do with stem cells and MS:


Dear Me: A Letter to Myself on a Bad Day:



 · Oct 21
Did you know that dysphagia (or difficulty swallowing) could be a symptom of MS?

Tips for Managing MS Cramps and Spasms: Apply an ice pack to your muscles:



Multiple Sclerosis 101: Understanding the Immune System:




The Swank Diet, Calcium EAP, and Bee Venom Therapy!



Ever wonder why MS causes such a wide variety of symptoms? Don't miss this overview:


Management of anxiety, mood swings, pseudobulbar affect (PBA), and stress:


Exercise. Easier said then done. Challenges faced while crawling along the road to better living through movement.


I've learned to be my own advocate. Know whats best for you. Speak up. If you don't like something, say something.


Exercise can help with managing MS Fatigue. Even 10 min/day, can add to your energy reserves:




Almost all of my old hopes, dreams, & desires stand frozen, as if parts of my very soul have been put on ice:




MS Sleep Hygiene Tip: Set a regular time to go to bed and stick with it.


We may be fatigued, but it doesn’t necessarily mean our muscle strength is weaker. Learn more:


Living with MS is like riding a roller coaster with many ups and downs, twists and turns, sudden starts and stops:
















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