Multiple Sclerosis Discovery Forum

New drug added to the Drug-Development Pipeline We recently added a new drug to our Drug-Development Pipeline database. The drug, ATX-MS-1467, is an immunomodulator. Click the link above to view.

News & Future Directions   No Causal Link Found Between Vaccines and MS A large case-control study showed no causal link between current vaccines and the risk of MS or other CNS demyelinating disease, but there was a short-term increased risk in younger patients. Multiple Sclerosis Discovery Podcast -- Episode 18 with Dr. Samuel Ludwin In the latest episode of the MSDF podcast, we interview Dr. Samuel Ludwin about new approaches to remyelinating therapies. We post each episode at http://www.msdiscovery.org/news/podcasts. You may also subscribe to the podcast via iTunes or your favorite podcast app. To subscribe in iTunes, simply go to the iTunes store, search "Multiple Sclerosis Discovery," click on the link to the show, and then click "subscribe." MS Research Roundup: October 28, 2014 Rare Brain Disease Death Reported for Dimethyl Fumarate; Using Arms and Legs After Spinal Cord Injury; How to Sell Bogus Drugs MS Research Roundup: October 22, 2014 A Better CRISPR Mouse; Number Needed to Treat; Ann Romney to Raise $50M for Neuroscience Research

MS Patient, Ph.D.   MS Patient, Ph.D.: Lightning (and the Ice Bucket Challenge) Doesn’t Strike Twice The ice bucket challenge has raised $100 million for the Amyotrophic Lateral Sclerosis Association; should the multiple sclerosis community try to copy this campaign?

Forums & Comments   Share your thoughts about any of MS Discovery Forum's articles and discussion topics. Your viewpoints will enrich the site for everyone. Recent comments have come from Bob Finn, Barbara van Amerongen, and B. Krone.

Papers   Visit Papers of the Week for the latest citations from PubMed, and then post a comment or read a colleague's. View Editors' Picks selections and Classic Papers, suggested by members of the community. Submit your own suggestions to help build this catalog of milestone papers.

Professional Resources   Visit the site’s Professional Resources section to access our listings of • Meetings and Events   NEW! UCSF Seminar: "The needle in the haystack: Searching for target antigens of the adaptive immune response in MS." - Oct 31   American Academy of Neurology Fall Conference 2014  - Oct 31-Nov 2   12th International Society of Neuroimmunology Congress - Nov 9-13   Neuroscience 2014 - Nov 15-19   Blood Brain Barrier Meeting - Dec 10-13   Keystone Symposium: Viral Immunity - Jan 11-16     Keystone Symposium: Neuroinflammation in Diseases of the Central Nervous System - Jan 25-30 (Abstract Submission Deadline Oct 23)  Keystone Symposium: Autoimmunity and Tolerance - Feb 3-8 (Abstract Submission Deadline Nov 4)   Keystone Symposium: Neuroepigenetics - Feb 22-26 (Abstract Submission Deadline Nov 19)   Glial Biology: Functional Interactions Among Glia & Neurons (Gordon Research Seminar) - Feb 28-Mar 1 (Abstract Submission Deadline Jan 31)   NEW! Keystone Symposium: Gut Microbiota Modulation of Host Physiology: The Search for Mechanism - Mar 1-6 (Abstract submission deadline Dec 2)   NEW! Keystone Symposium: Dendritic Cells and Macrophages Reunited - Mar 8-13 (Abstract submission deadline Dec 10)   American Society for Neurochemistry 46th Annual Meeting - Mar 14-18 (Early Registration Deadline Jan 30 )   2015 Annual Meeting of the Consortium of the Multiple Sclerosis Centers - May 27-30 (Abstract submission deadline Jan 9)   FOCIS 2015 (Federation of Clinical Immunology Societies) - Jun 24-27   ISN-APSN Biennial Meeting - Aug 23-27 Are we missing something? Post it to our website! Just go to the professional resources tab at msdiscovery.org, click on "Meetings and Events," and click the "Submit new item" button. Then simply log in and post your meeting. We're happy even to list departmental seminars. If you prefer, you can also email your items to editor@msdiscovery.org. • Funding Opportunities   Round 2 Grant Awards from the International Progressive MS Alliance - Application period opens Nov 3   ECTRIMS Multiple Sclerosis Clinical Training Fellowship Programme - Application due Dec 1   ECTRIMS Postdoctoral Research Fellowship Exchange Programme - Application due Dec 1   National MS Society: Health Care Delivery And Policy Research Contracts - Application due Jan 7, 2015   ECTRIMS Multiple Sclerosis Nurse Training Fellowship Programme - Application due Feb 1, 2015   ECTRIMS-MAGNIMS Fellowship in Magnetic Resonance Imaging in MS - Application due Feb 1, 2015   • Jobs   Mellen Center MS Neurologist - Las Vegas, NV & Weston, FL   MS Neurologist: Massachusetts General Hospital   Research Associate: Tisch MS Research Center of New York • Bulletin Board   Seeking Nominations: Dystel Prize for MS Research - Deadline Oct 23

Research Resources   • The Data Visualization section presents MS-related data in new ways, making it easy for viewers to discover unexpected relationships. • The Drug-Development Pipeline consolidates key information about compounds under investigation for therapeutic use. NEW! This past week, we added 1 new trial, we updated information on 2 other trials, and we've added 11 other pieces of information. The drugs with important additions and changes are dalfampridine, dimethyl fumarate, fingolimod, interferon beta-1a, interferon beta-1b, mitoxantrone, natalizumab, and teriflunomide. We've also added a new entry for ATX-MS-1467, which contains information on 3 trials as well as 23 other pieces of information. In summary, for the month of October we added 6 new trials, we updated information on 8 other trials, and we added 85 other pieces of information. The drugs with important additions and changes are ATX-MS-1467, daclizumab, dalfampridine, dimethyl fumarate, fingolimod, glatiramer acetate, interferon beta-1a, interferon beta-1b, laquinimod, masitinib, mitoxantrone, natalizumab, rituximab, and teriflunomide. • Tissue Repositories lists features of the world’s tissue repositories and brain banks, including rules of engagement and contact information. Let us know about additional repositories to include. • Animal Models summarizes the promises and pitfalls of animal models used in MS research. NEW! We recently added a new animal model to our collection: the Zebrafish. • Clinical Trials lists sources of information about MS clinical trials.

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