People with multiple sclerosis experience a form of overwhelming lassitude or tiredness that can occur at any time of the day, for any duration, and that does not necessarily recur in a recognizable pattern for any given patient, referred to as "neurological fatigue".
Chronic fatigue
Prolonged fatigue is a self-reported, persistent (constant) fatigue lasting at least one month. Chronic fatigue is a self-reported fatigue lasting at least six consecutive months. Chronic fatigue may be either persistent or relapsing. Chronic fatigue is a symptom of many diseases and conditions. Some major categories of diseases that feature fatigue include:
Autoimmune diseases such as celiac disease, lupus, multiple sclerosis, myasthenia gravis, and spondyloarthropathy
Link: http://en.wikipedia.org/wiki/Neurological_fatigue
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