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"In the midst of winter I finally learned that there was in me an invincible summer."

- Alert Camus








Friday, July 18, 2014

Alertec use for Multiple sclerosis

Modafinil is a vigilance promoting drug (or eugeroic) that is approved by the United States' Food and Drug Administration (FDA) for treatment of the wakefulness disorders of narcolepsyshift work sleep disorder and excessive daytime sleepiness associated with obstructive sleep apnea. In English-speaking countries it is sold under the brand names: Alertec (CA)Modavigil (AUNZ) and Provigil (IEZAUKUS).


Multiple sclerosis

Modafinil has also found off-label use with the neurological fatigue reported by some with multiple sclerosis.[51] In 2000, Cephalon conducted a study to evaluate modafinil as a potential treatment for MS-related fatigue. A group of 72 people with MS of varying degrees of severity tested two different doses of modafinil and an inactive placebo over nine weeks. Fatigue levels were self-evaluated on standardized scales. Participants taking a lower dose of modafinil reported feeling less fatigued and there was a statistically significant difference in fatigue scores for the lower dose versus the placebo. The higher dose of modafinil was not reported to be significantly more effective.



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