This is positive news and anything good you can say about m.s. is ok with me. Brain plasticity studies have shown that we can strengthen against cognitive decline by doing "brain exercises" and this study seems to indicate we can bolster our brains by mental stimulation - the protective effect of intellectual enrichment in MS. was previously documented. Genetic inheritance is beyond our control.
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Brain Reserve Found To Independently Protect Against Cognitive Decline In Multiple Sclerosis
27 Jun 2013
U.S. and Italian researchers have determined that brain reserve, as well as cognitive reserve, independently protects against cognitive decline in multiple sclerosis (MS). Their article, "Brain reserve and cognitive reserve in multiple sclerosis: What you've got and how you use it", was published in Neurology (Neurology 2013;80:2186-2193). Authors James Sumowski, PhD, Victoria Leavitt, PhD, and John DeLuca, PhD, are with Kessler Foundation in West Orange, NJ. Maria Rocca, MD, Gianna Riccitelli, PhD, Giancarlo Comi, MD, and Massimo Filippi, MD, are with San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
"Our research interests focus on why many people with MS suffer cognitive impairment, while others with MS withstand considerable disease progression without cognitive decline," said Dr. DeLuca, VP for Research & Training at Kessler Foundation. "With our colleagues in Milan, we explore factors associated with lack of cognitive decline despite marked changes on imaging studies."
Brain Reserve Found To Independently Protect Against Cognitive Decline In Multiple Sclerosis
27 Jun 2013
U.S. and Italian researchers have determined that brain reserve, as well as cognitive reserve, independently protects against cognitive decline in multiple sclerosis (MS). Their article, "Brain reserve and cognitive reserve in multiple sclerosis: What you've got and how you use it", was published in Neurology (Neurology 2013;80:2186-2193). Authors James Sumowski, PhD, Victoria Leavitt, PhD, and John DeLuca, PhD, are with Kessler Foundation in West Orange, NJ. Maria Rocca, MD, Gianna Riccitelli, PhD, Giancarlo Comi, MD, and Massimo Filippi, MD, are with San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
"Our research interests focus on why many people with MS suffer cognitive impairment, while others with MS withstand considerable disease progression without cognitive decline," said Dr. DeLuca, VP for Research & Training at Kessler Foundation. "With our colleagues in Milan, we explore factors associated with lack of cognitive decline despite marked changes on imaging studies."
In this study, 62 patients with MS (41 relapsing-remitting MS, 21 secondary progressive MS) had MRIs to estimate brain reserve and disease burden. Early-life cognitive leisure was measured as a source of cognitive reserve. Cognitive status was measured with tasks of cognitive efficiency and memory.
Dr. Sumowski, principal author/ investigator, commented on the importance of the study, saying, "We demonstrated for the first time that larger maximal lifetime brain growth (which is heritable) and early life mental stimulation (e.g., reading, games, hobbies) independently and differentially protect against cognitive decline in MS. That is, genetics and life experience independently protect against cognitive decline in persons with MS."
Dr. Sumowski, principal author/ investigator, commented on the importance of the study, saying, "We demonstrated for the first time that larger maximal lifetime brain growth (which is heritable) and early life mental stimulation (e.g., reading, games, hobbies) independently and differentially protect against cognitive decline in MS. That is, genetics and life experience independently protect against cognitive decline in persons with MS."
Foundation scientists have previously documented the protective effect of intellectual enrichment in MS.
References:
Dr. Sumowski is a research scientist in Neuropsychology & Neuroscience Research, under the directorship of Nancy Chiaravalloti, PhD. Drs. Sumowski, Leavitt and DeLuca are on the faculty of the department of physical medicine and rehabilitation at UMDNJ-New Jersey Medical School.
Relevant publications:
Sumowski JF, Wylie GR, Chiaravalloti N, DeLuca J. Intellectual enrichment lessens the effect of brain atrophy on learning and memory in multiple sclerosis. Neurology. 2010 Jun 15;74(24):1942-5.
Sumowski JF, Wylie GR, Leavitt VM, Chiaravalloti ND, DeLuca J. Default network activity is a sensitive and specific biomarker of memory in multiple sclerosis. Mult Scler. 2013 Feb;19(2):199-208.
Kessler Foundation
Citations:
Please use one of the following formats to cite this article in your essay, paper or report:
MLA
Kessler Foundation. "Brain Reserve Found To Independently Protect Against Cognitive Decline In Multiple Sclerosis." Medical News Today. MediLexicon, Intl., 27 Jun. 2013. Web.
1 Jul. 2013.
APA
Kessler Foundation. (2013, June 27). "Brain Reserve Found To Independently Protect Against Cognitive Decline In Multiple Sclerosis." Medical News Today. Retrieved from
http://www.medicalnewstoday.com/releases/262504.php.
Please note: If no author information is provided, the source is cited instead.
Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. For more information, please read our terms and conditions.
Weekly newsletter e-mails available at: http://www.medicalnewstoday.com/newsletters.php
Source: http://www.medicalnewstoday.com/releases/262504.php
References:
Dr. Sumowski is a research scientist in Neuropsychology & Neuroscience Research, under the directorship of Nancy Chiaravalloti, PhD. Drs. Sumowski, Leavitt and DeLuca are on the faculty of the department of physical medicine and rehabilitation at UMDNJ-New Jersey Medical School.
Relevant publications:
Sumowski JF, Wylie GR, Chiaravalloti N, DeLuca J. Intellectual enrichment lessens the effect of brain atrophy on learning and memory in multiple sclerosis. Neurology. 2010 Jun 15;74(24):1942-5.
Sumowski JF, Wylie GR, Leavitt VM, Chiaravalloti ND, DeLuca J. Default network activity is a sensitive and specific biomarker of memory in multiple sclerosis. Mult Scler. 2013 Feb;19(2):199-208.
Kessler Foundation
Citations:
Please use one of the following formats to cite this article in your essay, paper or report:
MLA
Kessler Foundation. "Brain Reserve Found To Independently Protect Against Cognitive Decline In Multiple Sclerosis." Medical News Today. MediLexicon, Intl., 27 Jun. 2013. Web.
1 Jul. 2013.
APA
Kessler Foundation. (2013, June 27). "Brain Reserve Found To Independently Protect Against Cognitive Decline In Multiple Sclerosis." Medical News Today. Retrieved from
http://www.medicalnewstoday.com/releases/262504.php.
Please note: If no author information is provided, the source is cited instead.
Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. For more information, please read our terms and conditions.
Weekly newsletter e-mails available at: http://www.medicalnewstoday.com/newsletters.php
Source: http://www.medicalnewstoday.com/releases/262504.php
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